Article

Genetic and chemical inhibition of autophagy in zebrafish induced myeloproliferation

2021-06-14

Abstract excerpt

Autophagy is an evolutionary conserved and dynamic lysosomal degradation process for cellular homeostasis and remodelling, which is essential for the development and maintenance of different hematopoietic fates. However, the roles of autophagy in definitive hematopoiesis remain elusive. Here, we exploited zebrafish ( Danio rerio ) to investigate the effect of knocking-out unc-51 like autophagy activating kinase 1...

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Literature Corpus work: 2416e302-9834-5358-8db6-083f863e5a07
DOI: 10.1101/2021.06.14.448302

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