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Article

Autophagy as a Regulatory Component of Erythropoiesis

13 Feb 2015

Abstract excerpt

Autophagy is a process that leads to the degradation of unnecessary or dysfunctional cellular components and long-lived protein aggregates. Erythropoiesis is a branch of hematopoietic differentiation by which mature red blood cells (RBCs) are generated from multi-potential hematopoietic stem cells (HSCs). Autophagy plays a critical role in the elimination of mitochondria, ribosomes and other organelles during...

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PMID: 25689426
DOI: 10.3390/ijms16024083

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