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Isthmin 1 (ism1) is required for normal hematopoiesis in developing zebrafish

14 May 2018

Abstract excerpt

Hematopoiesis is an essential and highly regulated biological process that begins with hematopoietic stem cells (HSCs). In healthy organisms, HSCs are responsible for generating a multitude of mature blood cells every day, yet the molecular pathways that instruct HSCs to self-renew and differentiate into post-mitotic blood cells are not fully known. To understand these molecular pathways, we investigated novel...

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Share to Epigenetics and DNA Methylation
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PMID: 29758043
DOI: 10.1371/journal.pone.0196872

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