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Article

Central and Peripheral Regulation of Food Intake and Physical Activity: Pathways and Genes

27 Nov 2008

Abstract excerpt

A changing environment and lifestyle on the background of evolutionary engraved and perinatally imprinted physiological response patterns is the foremost explanation for the current obesity epidemic. However, it is not clear what the mechanisms are by which the modern environment overrides the physiological controls of appetite and homeostatic body-weight regulation. Food intake and energy expenditure are...

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PMID: 19190620
DOI: 10.1038/oby.2008.511

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