Article

Nuclear Receptor 5A2 Regulation of <i>Agrp</i> underlies Olanzapine-induced Hyperphagia

2022-02-18

Abstract excerpt

<h4>Summary/Abstract</h4> Antipsychotic (AP) drugs are highly efficacious treatments for psychiatric disorders, but a serious side effect of their use is excessive weight gain and subsequent development of metabolic disease. Increased food intake is the underlying driver of AP-induced weight gain, although the underlying mechanisms remain unknown. In previous studies, we identified hypothalamic genes whose expres...

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Literature Corpus work: 0762f1fe-177d-5506-8e68-d9085134252d
DOI: 10.1101/2022.02.15.480590

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