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Relationship of Klotho with cognition and dementia: Results from the NHANES 2011–2014 and Mendelian randomization study

1 Nov 2023

Abstract excerpt

The relationships of Klotho levels with cognition and dementia are poorly understood. This study aimed to investigate the association between Klotho levels and cognitive function and to determine causality between Klotho and dementia using Mendelian randomization (MR). Based on data from the National Health and Nutrition Survey (NHANES) 2011-2014, this study consisted of 1875 older adults aged 60-79 years....

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PMID: 37914711
DOI: 10.1038/s41398-023-02632-x

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