Article
Proximity Mapping of Ciliary Proteins by BioID.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024
Iazzi Melissa, St-Germain Jonathan, Acharya Saujanya, Raught Brian, Gupta Gagan D
Abstract excerpt
The primary cilium is a highly conserved microtubule-based organelle present in most vertebrate cell types. Mutations in ciliary protein genes can lead to dysfunctional or absent cilia and are the cause of a large group of heterogeneous diseases known as ciliopathies. ARL13B is a member of the ARF family of regulatory GTPases and is highly enriched on the ciliary membrane. The absence of ARL13B disrupts cilia...
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