Landscape of nuclear transport receptor cargo specificity.

Abstract excerpt

Nuclear transport receptors (NTRs) recognize localization signals of cargos to facilitate their passage across the central channel of nuclear pore complexes (NPCs). About 30 different NTRs constitute different transport pathways in humans and bind to a multitude of different cargos. The exact cargo spectrum of the majority of NTRs, their specificity and even the extent to which active nucleocytoplasmic transport...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Active Transport, Cell Nucleus
• Share to Biotinylation