Article

Identification of TbRP2-interacting proteins using proximity-dependent biotinylation (BioID)

2017-01-01

Abstract excerpt

The protein RP2 is a tubulin cofactor C-domain containing protein with important roles in ciliogenesis. In humans, mutations in the RP2 gene are associated with 10-15% of cases of X-linked retinitis pigmentosa; a devastating disease characterised by progressive degeneration of retinal photoreceptors. Although XRP2 was initially proposed to function as a GTPase-activating protein (GAP) for tubulin, evidence now sug...

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Literature Corpus work: 0753d4fd-5ae5-5e1b-9f3e-69ccfdb52d2b
DOI: 10.17635/lancaster/thesis/206

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