Article

Unraveling the Intricate Cargo-BBSome Coupling Mechanism at the Ciliary Tip

2022-11-03

Abstract excerpt

Certain ciliary transmembrane and membrane-tethered signaling proteins migrate from the ciliary tip to base via retrograde intraflagellar transport (IFT), essential for maintaining their ciliary dynamics to enable cells to sense and transduce extracellular stimuli inside the cell. During this process, the BBSome functions as an adaptor between retrograde IFT trains and these signaling protein cargoes. The Arf-like...

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Literature Corpus work: f070376e-75d1-57c7-9d73-80dec0e41362
DOI: 10.1101/2022.11.02.514950

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