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Article

Data-adaptive and pathway-based tests for association studies between somatic mutations and germline variations in human cancers.

Genetic epidemiology - 1 Dec 2023

Chen Zhongyuan, Liang Han, Wei Peng

Abstract excerpt

Cancer is a disease driven by a combination of inherited genetic variants and somatic mutations. Recently available large-scale sequencing data of cancer genomes have provided an unprecedented opportunity to study the interactions between them. However, previous studies on this topic have been limited by simple, low statistical power tests such as Fisher's exact test. In this paper, we design data-adaptive and...

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PMID: 37822029
DOI: 10.1002/gepi.22537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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