Article

Unveiling Candidate Drivers in Cancer Progression Using Somatic-IV Analysis

2025-02-26

Abstract excerpt

<h4>Motivation</h4> Identifying causal drivers of cancer progression is crucial for developing effective anti-cancer therapies. However, disentangling causality from correlation remains challenging due to confounding factors within the complex genetic and transcriptomic landscapes of cancer. <h4>Results</h4> To address this challenge, we introduce the Somatic Instrumental Variable analysis (Somatic-IV), which in...

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Literature Corpus work: 518567e4-b6e0-572f-9068-27abde965efb
DOI: 10.1101/2025.02.20.638369

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