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Article

Reconfiguring phosphorylation signaling by genetic polymorphisms affects cancer susceptibility.

Journal of molecular cell biology - 1 Jun 2015

Wang Yongbo, Cheng Han, Pan Zhicheng, Ren Jian, Liu Zexian, Xue Yu

Abstract excerpt

Large-scale sequencing has characterized an enormous number of genetic variations (GVs), and the functional analysis of GVs is fundamental to understanding differences in disease susceptibility and therapeutic response among and within populations. Using a combination of a sequence-based predictor with known phosphorylation and protein-protein interaction information, we computationally detected 9606 potential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25722345
DOI: 10.1093/jmcb/mjv013

Genes

EGFR
IRS1
RAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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