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Association between HLA alleles and beta-lactam antibiotics-related severe cutaneous adverse reactions

19 Sept 2023

Abstract excerpt

Introduction: Beta-lactam antibiotics are one of the most common causes of antibiotics-related severe cutaneous adverse reactions (SCARs) including Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), drug reactions with eosinophilia and systemic symptoms (DRESS), and acute generalized exanthematous pustulosis (AGEP). Recent evidence demonstrated that the human leukocyte antigen (HLA) polymorphisms...

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PMID: 37795024
DOI: 10.3389/fphar.2023.1248386

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