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Genetics of Severe Cutaneous Adverse Reactions

15 Jul 2021

Abstract excerpt

Severe cutaneous adverse reactions (SCARs) including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug rash with eosinophilia and systemic symptoms (DRESS) are T cells-mediated life-threatening immune reactions, most commonly induced by drug. The last decade has seen significant progress in SCARs research. Recent studies have unveiled the pathogenesis of SCARs involved in susceptible...

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PMID: 34336873
DOI: 10.3389/fmed.2021.652091

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