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Article

HLA Pharmacogenetic Markers of Drug Hypersensitivity in a Thai Population

6 Aug 2018

Abstract excerpt

Severe cutaneous adverse drug reactions (SCARs) including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reactions with eosinophilia and systemic symptoms (DRESS) are potentially life-threatening cutaneous reactions caused by several drugs. Recently, a number of genes encoding for human antigen presenting proteins, HLA alleles, have been discovered as valid pharmacogenetic markers for...

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PMID: 30127801
DOI: 10.3389/fgene.2018.00277

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