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Article

Association of HLA-A and HLA-B Alleles with Lamotrigine-Induced Cutaneous Adverse Drug Reactions in the Thai Population

29 Nov 2017

Abstract excerpt

Background: Lamotrigine (LTG) is commonly used for treatment of epilepsy and bipolar disorder. It is one of the common cause of cutaneous adverse reactions (CADR). Clinical symptoms of LTG-induced CADR range from maculopapular exanthema (MPE) to severe cutaneous adverse reactions (SCAR). This study aimed to determine the association of the LTG-induced cutaneous adverse drug reaction (CADR) with HLA alleles in...

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Identifiers

PMID: 29238301
DOI: 10.3389/fphar.2017.00879

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