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Article

Genotyping HLA alleles to predict the development of Severe cutaneous adverse drug reactions (SCARs): state-of-the-art.

Expert opinion on drug metabolism & toxicology - 1 Sept 2021

Jantararoungtong Thawinee, Tempark Therdpong, Koomdee Napatrupron, Medhasi Sadeep, Sukasem Chonlaphat

Abstract excerpt

Introduction: Pharmacogenomics has great potential in reducing drug-induced severe cutaneous adverse drug reactions (SCARs). Pharmacogenomic studies have revealed an association between HLA genes and SCARs including acute generalized exanthematous pustulosis (AGEP), drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN).Areas covered:...

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Identifiers

PMID: 34148467
DOI: 10.1080/17425255.2021.1946514

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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