Article
Transcriptomics and proteomics reveal distinct biology for lymph node metastases and tumour deposits in colorectal cancer
4 Oct 2023
Abstract excerpt
Both lymph node metastases (LNMs) and tumour deposits (TDs) are included in colorectal cancer (CRC) staging, although knowledge regarding their biological background is lacking. This study aimed to compare the biology of these prognostic features, which is essential for a better understanding of their role in CRC spread. Spatially resolved transcriptomic analysis using digital spatial profiling was performed on...
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