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Transcriptome-wide association study-derived genes as potential visceral adipose tissue-specific targets for type 2 diabetes

4 Aug 2023

Abstract excerpt

AIMS/HYPOTHESIS: This study aimed to assess the causal relationship between visceral obesity and type 2 diabetes and subsequently to screen visceral adipose tissue (VAT)-specific targets for type 2 diabetes. METHODS: We examined the causal relationship between VAT and type 2 diabetes using bidirectional Mendelian randomisation (MR) followed by multivariable MR. We conducted a transcriptome-wide association study...

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PMID: 37540242
DOI: 10.1007/s00125-023-05978-5

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