Article
Targeted mutation and inactivation of the kinesin light chain 3 protein-encoding gene have no impact on mouse fertility†.
Biology of reproduction - 13 Jan 2024
Daniel-Carlier Nathalie, Castille Johan, Passet Bruno, Vilotte Marthe, Le Danvic Christelle, Jaffrezic Florence, Beauvallet Christian, Péchoux Christine, Capitan Aurélien, Vilotte Jean-Luc
Abstract excerpt
The kinesin light chain 3 protein (KLC3) is the only member of the kinesin light chain protein family that was identified in post-meiotic mouse male germ cells. It plays a role in the formation of the sperm midpiece through its association with both spermatid mitochondria and outer dense fibers (ODF). Previous studies showed a significant correlation between its expression level and sperm motility and...
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