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Article

Spermatogenic Cell-Specific Gene Mutation in Mice via CRISPR-Cas9.

Journal of genetics and genomics = Yi chuan xue bao - 20 May 2016

Bai Meizhu, Liang Dan, Wang Yinghua, Li Qing, Wu Yuxuan, Li Jinsong

Abstract excerpt

Tissue-specific knockout technology enables the analysis of the gene function in specific tissues in adult mammals. However, conventional strategy for producing tissue-specific knockout mice is a time- and labor-consuming process, restricting rapid study of the gene function in vivo. CRISPR-Cas9 system from bacteria is a simple and efficient gene-editing technique, which has enabled rapid generation of gene...

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Identifiers

PMID: 27210043
DOI: 10.1016/j.jgg.2016.02.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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