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Article

AU040320 deficiency leads to disruption of acrosome biogenesis and infertility in homozygous mutant mice.

Scientific reports - 10 Jul 2018

Guidi Luiz G, Holloway Zoe G, Arnoult Christophe, Ray Pierre F, Monaco Anthony P, Molnár Zoltán, Velayos-Baeza Antonio

Abstract excerpt

Study of knockout (KO) mice has helped understand the link between many genes/proteins and human diseases. Identification of infertile KO mice provides valuable tools to characterize the molecular mechanisms underlying gamete formation. The KIAA0319L gene has been described to have a putative association with dyslexia; surprisingly, we observed that homozygous KO males for AU040320, KIAA0319L ortholog, are...

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Identifiers

PMID: 29991750
DOI: 10.1038/s41598-018-28666-6
PMCID: PMC6039479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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