Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Coexistence of hepatitis B virus quasispecies enhances viral replication and the ability to induce host antibody and cellular immune responses.

Journal of virology - 1 Aug 2014

Cao Liang, Wu Chunchen, Shi Hui, Gong Zuojiong, Zhang Ejuan, Wang Hui, Zhao Kaitao, Liu Shuhui, Li Songxia, Gao Xiuzhu, Wang Yun, Pei Rongjuan, Lu Mengji, Chen Xinwen

Abstract excerpt

UNLABELLED: Hepatitis B virus (HBV) quasispecies contain a large number of variants that serve as a reservoir for viral selection under antiviral treatment and the immune response, leading to the acute exacerbation and subsequent development of liver failure. However, there is no clear experimental evidence for a significant role of HBV quasispecies in viral pathogenesis. In the present study, HBV sequences were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Models, Animal
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B

Share to Hepatitis B Antibodies

Share to Hepatitis B virus

Share to Immunity, Cellular

Share to Sequence Analysis, DNA

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 24850745
DOI: 10.1128/JVI.01123-14
PMCID: PMC4135971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Coexistence of hepatitis B virus quasispecies enhances viral replication and the ability to induce host antibody and cellular immune responses.PMID 24850745Read ↗

Molecular Mechanisms during Hepatitis B Infection and the Effects of the Virus Variability.Semantic proximity Read ↗

Susceptibility of different hepatitis B virus isolates to interferon-alpha in a mouse model based on hydrodynamic injection.Semantic proximity Read ↗

Evolution of full-length genomes of HBV quasispecies in sera of patients with a coexistence of HBsAg and anti-HBs antibodies.Semantic proximity Read ↗

Type I Interferon Signaling Prevents Hepatitis B Virus-Specific T Cell Responses by Reducing Antigen Expression.Semantic proximity Read ↗

Inhibition of hepatitis B virus (HBV) gene expression and replication by HBx gene silencing in a hydrodynamic injection mouse model with a new clone of HBV genotype B.Semantic proximity Read ↗

Hepatitis B Virus DNA Integration: In Vitro Models for Investigating Viral Pathogenesis and PersistenceSemantic proximity Read ↗

The Hepatitis B Virus Genotype Affects the Persistence of Viral Replication in Immunodeficient NOG Mice.Semantic proximity Read ↗

Phenotyping hepatitis B virus variants: from transfection towards a small animal in vivo infection model.Semantic proximity Read ↗

DNA vaccine cocktail expressing genotype A and C HBV surface and consensus core antigens generates robust cytotoxic and antibody responses in mice and Rhesus macaques.Semantic proximity Read ↗

Influence of hepatitis B virus genotypes on the intra- and extracellular expression of viral DNA and antigens.Semantic proximity Read ↗

Phenotypic mixing of rodent but not avian hepadnavirus surface proteins into human hepatitis B virus particles.Semantic proximity Read ↗

Infection courses, virological features and IFN-α responses of HBV genotypes in cell culture and animal models.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.