Article
Change in hepatitis B virus large surface antigen variant prevalence 13 years after implementation of a universal vaccination program in China.
Journal of virology - 1 Nov 2013
Bian Tao, Yan Hongxia, Shen Liping, Wang Feng, Zhang Shuang, Cao Yanqiang, Zhang Shuo, Zhang Yong, Bi Shengli
Abstract excerpt
A nationwide hepatitis B virus (HBV) vaccination program was implemented in China starting in 1992. To study the change in HBV variant prevalence with massive immunization, large HBV surface protein (LHBs) genes from HBV surface antigen (HBsAg)-positive sera were amplified and sequenced. The prevalences of LHBs mutants were compared between the 1992 and 2005 surveys in child and adult groups. The prevalence of...
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