Article
Hepatitis B virus vaccine breakthrough infection: surveillance of S gene mutants of HBV.
Acta virologica - 1 Jan 2000
Qin Y, Liao P
Abstract excerpt
Hepatitis B (HB) is a worldwide public health problem, closely related with liver cirrhosis and hepatocellular carcinoma (HCC). The implementation of universal hepatitis B virus (HBV) vaccination programs has led to significant reduction in incidence of acute and chronic HB, liver cirrhosis and HCC. However, this success is now being threatened by the discovery of HBV vaccine breakthrough infection caused by the...
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