Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys

22 Sept 2023

Abstract excerpt

Tauopathy, characterized by the hyperphosphorylation and accumulation of the microtubule-associated protein tau, and the accumulation of Aβ oligomers, constitute the major pathological hallmarks of Alzheimer's disease. However, the relationship and causal roles of these two pathological changes in neurodegeneration remain to be defined, even though they occur together or independently in several neurodegenerative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Nerve injury and regeneration
Share to Neuroinflammation and Neurodegeneration Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37735155
DOI: 10.1038/s41392-023-01601-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeysPMID 37735155Read ↗

Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein.Semantic proximity Read ↗

Combining P301L and S320F tau variants produces a novel accelerated model of tauopathySemantic proximity Read ↗

GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils.Semantic proximity Read ↗

A non-human primate model with Alzheimer’s disease-like pathology induced by hippocampal overexpression of human tauSemantic proximity Read ↗

Characterization of a novel transgenic rat carrying human tau with mutation P301L.Semantic proximity Read ↗

A nonhuman primate model with Alzheimer's disease-like pathology induced by hippocampal overexpression of human tauSemantic proximity Read ↗

Transgenic Monkey Model of the Polyglutamine Diseases Recapitulating Progressive Neurological Symptoms.Semantic proximity Read ↗

Early Parkinson's disease symptoms in -synuclein transgenic monkeysSemantic proximity Read ↗

Cre-inducible Adeno Associated Virus-mediated Expression of P301L Mutant Tau Causes Motor Deficits and Neuronal Degeneration in the Substantia Nigra.Semantic proximity Read ↗

Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines.Semantic proximity Read ↗

Viral Delivery of Non-Mutated Human Truncated Tau to Neurons Recapitulates Key Features of Human Tauopathy in Wild-Type Mice.Semantic proximity Read ↗

Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer’s disease or corticobasal degeneration brainsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.