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A nonhuman primate model with Alzheimer's disease-like pathology induced by hippocampal overexpression of human tau

2023-10-19

Abstract excerpt

<h4>Background: </h4> Alzheimer's disease (AD) is one of the most burdening diseases of the century with no disease-modifying treatment at this time. Nonhuman primates (NHPs) share genetic, anatomical and physiological similarities with humans, making them ideal model animals for investigating the pathogenesis of AD and potential therapies. However, the use of NHPs in AD research has been hindered by the paucity o...

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Literature Corpus work
d813fdda-2df6-5b5f-a519-106b7c33280d
DOI
10.21203/rs.3.rs-3456611/v1
Open publication

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A nonhuman primate model with Alzheimer's disease-like pathology induced by hippocampal overexpression of human tauDOI 10.21203/rs.3.rs-3456611/v1
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