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A non-human primate model with Alzheimer’s disease-like pathology induced by hippocampal overexpression of human tau

2022-10-27

Abstract excerpt

Alzheimer’s disease (AD) is one of the most burdening diseases of the century with no disease-modifying treatment yet. Non-human primates (NHPs) share genetic, anatomical and physiological similarities with humans, making them an ideal model for investigating the pathogenesis and therapeutics of AD. However, the applications of NHPs in AD research have been hindered by the paucity of spontaneous or induced monkey...

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Literature Corpus work
bc04599a-4f72-5cfa-8699-a2e053cd9a2f
DOI
10.1101/2022.10.26.513832
Open publication

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A non-human primate model with Alzheimer’s disease-like pathology induced by hippocampal overexpression of human tauDOI 10.1101/2022.10.26.513832
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