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Article

Mutations in the C-terminal region of the bacteriophage exclusion protein PglX can selectively inactivate restriction in Salmonella.

Journal of bacteriology - 26 Oct 2023

Wozniak Christopher E, Hughes Kelly T, Liou Theodore G

Abstract excerpt

Salmonella enterica serovar Typhimurium strain LT2 is protected by two DNA restriction-modification systems (HsdRMS and Mod-Res) and a Type I bacteriophage exclusion (BREX) system (BrxA-L). The LB5000 strain was constructed to inactivate restriction but not methylation in all three systems and has been available for decades (L. R. Bullas and J. I. Ryu, J Bacteriol 156:471-474, 1983,...

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Identifiers

PMID: 37730541
DOI: 10.1128/jb.00207-23
PMCID: PMC10601704

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Source receipt: pubmed, retrieved 7 Sept 2026.

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