Article
A genetic dissection of the LlaJI restriction cassette reveals insights on a novel bacteriophage resistance system.
BMC microbiology - 28 Apr 2006
O'Driscoll Jonathan, Heiter Daniel F, Wilson Geoffrey G, Fitzgerald Gerald F, Roberts Richard, van Sinderen Douwe
Abstract excerpt
BACKGROUND: Restriction/modification systems provide the dual function of protecting host DNA against restriction by methylation of appropriate bases within their recognition sequences, and restriction of foreign invading un-methylated DNA, such as promiscuous plasmids or infecting bacteriphage. The plasmid-encoded LlaJI restriction/modification system from Lactococcus lactis recognizes an asymmetric,...
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