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Article

Decreased CNNM2 expression in prefrontal cortex affects sensorimotor gating function, cognition, dendritic spine morphogenesis and risk of schizophrenia.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2024

Zhou Dan-Yang, Su Xi, Wu Yong, Yang Yongfeng, Zhang Luwen, Cheng Shumin, Shao Minglong, Li Wenqiang, Zhang Zhaohui, Wang Lu, Lv Luxian, Li Ming, Song Meng

Abstract excerpt

Genome-wide association studies (GWASs) have reported multiple single nucleotide polymorphisms (SNPs) associated with schizophrenia, yet the underlying molecular mechanisms are largely unknown. In this study, we aimed to identify schizophrenia relevant genes showing alterations in mRNA and protein expression associated with risk SNPs at the 10q24.32-33 GWAS locus. We carried out the quantitative trait loci (QTL)...

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Identifiers

PMID: 37715107
DOI: 10.1038/s41386-023-01732-y
PMCID: PMC10724213

Genes

CNNM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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