Plasmodium falciparum GCN5 plays a key role in regulating artemisinin resistance-related stress responses

Abstract excerpt

ABSTRACT Plasmodium falciparum causes the most severe malaria and is exposed to various environmental and physiological stresses in the human host. Given that GCN5 plays a critical role in regulating stress responses in model organisms, we aimed to elucidate PfGCN5’s function in stress responses in P. falciparum . The protein level of PfGCN5 was substantially induced under three stress conditions [heat shock, low...

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