Article
Proteogenomics: Key Driver for Clinical Discovery and Personalized Medicine.
Advances in experimental medicine and biology - 1 Jan 2016
Barbieri Ruggero, Guryev Victor, Brandsma Corry-Anke, Suits Frank, Bischoff Rainer, Horvatovich Peter
Abstract excerpt
Proteogenomics is a multi-omics research field that has the aim to efficiently integrate genomics, transcriptomics and proteomics. With this approach it is possible to identify new patient-specific proteoforms that may have implications in disease development, specifically in cancer. Understanding the impact of a large number of mutations detected at the genomics level is needed to assess the effects at the...
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