Article
Relative contribution of iron genes, dysmetabolism and hepatitis C virus (HCV) in the pathogenesis of altered iron regulation in HCV chronic hepatitis.
Haematologica - 1 Aug 2007
Valenti Luca, Pulixi Edoardo A, Arosio Paolo, Cremonesi Laura, Biasiotto Giorgio, Dongiovanni Paola, Maggioni Marco, Fargion Silvia, Fracanzani Anna Ludovica
Abstract excerpt
BACKGROUND AND OBJECTIVES: Hepatitis C virus (HCV) chronic hepatitis predisposes to iron overload, which negatively influences the prognosis of this infection. Since the underlying mechanisms of this iron overload are undefined, we analyzed the prevalence of altered iron parameters, and the relative contribution of viral, metabolic, and genetic factors in Italian patients. DESIGN AND METHODS: We studied the...
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