Article
Analysis of polymorphism and hepatic expression of duodenal cytochrome b in chronic hepatitis C.
Journal of gastroenterology and hepatology - 1 Feb 2017
Rudnicka Alina, Woziwodzka Anna, Wróblewska Anna, Rybicka Magda, Bielawski Krzysztof P, Sikorska Katarzyna, Bernat Agnieszka
Abstract excerpt
BACKGROUND AND AIM: Pathological iron overload is commonly found in chronic hepatitis C (CHC) patients and considered as a negative prognostic factor of the disease. A single nucleotide polymorphism (SNP) rs884409 in duodenal cytochrome b gene (CYBRD1) is implicated in the pathogenesis of hemochromatosis. In our study we investigated the impact of the CYBRD1 genotype and expression on iron overload in CHC...
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