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Article

Genetic variants of IFIH1 and DHX58 affect the chronicity of hepatitis C in the Chinese Han population.

PeerJ - 1 Jan 2023

Huang Peng, Wu Jing-Jing, Zhang Jin-Wei, Hou Yu-Qing, Zhu Ping, Yin Rong, Yu Rong-Bin, Zhang Yun, Yue Ming, Hou Wei

Abstract excerpt

Hepatitis C remains a major public health problem in the world. The host immune system plays a key role in viral clearance. This study aimed to investigate the connection between retinoic acid-inducible gene I-like (RIG-I-like) receptor gene polymorphism and hepatitis C chronicity in the Chinese Han population. The current study genotyped three SNPs (IFIH1 rs10930046 and DHX58 rs2074158, rs2074160) to assess...

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Share to East Asian People
Share to Hepacivirus
Share to Hepatitis C
Share to Interferon-Induced Helicase, IFIH1
Share to Polymorphism, Single Nucleotide
Share to RNA Helicases

Source

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Identifiers

PMID: 36743960
DOI: 10.7717/peerj.14740
PMCID: PMC9893905

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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