Article
Potentially functional genetic variants in ferroptosis-related CREB3 and GALNT14 genes predict survival of hepatitis B virus-related hepatocellular carcinoma.
Cancer medicine - 1 Jan 2024
Zhan Shicheng, Qiu Moqin, Wei Xueyan, Wei Junjie, Qin Liming, Jiang Binbin, Wen Qiuping, Chen Peiqin, Lin Qiuling, Wei Xiaoxia, Zhou Zihan, Jiang Yanji, Liang Xiumei, Li Runwei, Liu Yingchun, Yu Hongping
Abstract excerpt
BACKGROUND: Ferroptosis is a known crucial player in the development of cancers. However, the effect of single nucleotide polymorphisms (SNPs) in ferroptosis-related genes on survival in hepatitis B virus (HBV)-related hepatocellular carcinoma (HBV-HCC) patients remains unknown. METHODS: We used two-stage multivariable Cox proportional hazards regression analyses to estimate the associations between 48,774 SNPs...
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