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The heritability of blood‐based biomarkers related to risk of Alzheimer's disease in a population‐based sample of early old‐age men

25 Aug 2023

Abstract excerpt

Abstract INTRODUCTION Despite their increased application, the heritability of Alzheimer's disease (AD)–related blood‐based biomarkers remains unexplored. METHODS Plasma amyloid beta 40 (Aβ40), Aβ42, the Aβ42/40 ratio, total tau (t‐tau), and neurofilament light (NfL) data came from 1035 men 60 to 73 years of age (μ = 67.0, SD = 2.6). Twin models were used to calculate heritability and the genetic and...

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PMID: 37622539
DOI: 10.1002/alz.13407

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