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Nitrogen-Doped Graphene Quantum Dots as Electrochemiluminescence-Emitting Species for Sensitive Detection of KRAS G12C Mutation via PET-RAFT.

Chemistry (Weinheim an der Bergstrasse, Germany) - 21 Nov 2023

Ma Lele, Kang Le, Sun Yuzhi, Liu Jingwen, Yang Huaixia, Miao Mingsan

Abstract excerpt

The levels of KRAS G12C point mutation is recognized to be closely related to the earlier diagnosis of non-small cell lung cancer (NSCLC). Here, based on nitrogen-doped graphene quantum dots (NGQDs) and photo-induced electron/energy transfer reversible addition-fragment chain transfer (PET-RAFT) signal amplification strategy, we fabricated a novel electrochemiluminescence (ECL) biosensor for the detection of KRAS...

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PMID: 37622405
DOI: 10.1002/chem.202301602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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