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An electrochemiluminescence resonance energy transfer biosensor for the detection of circulating tumor DNA from blood plasma

21 Aug 2021

Abstract excerpt

A liquid biopsy is a noninvasive approach for detecting double-stranded circulating tumor DNA (ctDNA) of 90-320 nucleotides in blood plasma from patients with cancer. Most techniques employed for ctDNA detection are time consuming and require expensive DNA purification kits. Electrochemiluminescence resonance energy transfer (ECL-RET) biosensors exhibit high sensitivity, a wide response range, and are promising...

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PMID: 34522862
DOI: 10.1016/j.isci.2021.103019

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