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Article

Bioinformatics analysis of wild-type ParC and S79F, S79Y mutations in Streptococcus pneumoniae.

European review for medical and pharmacological sciences - 1 Aug 2023

Akgün Karapınar B, Oflaz O

Abstract excerpt

OBJECTIVE: S79Y and S79F mutations in ParC at the fluoroquinolone binding site confer resistance to quinolones in Streptococcus pneumoniae. The aim of this study was to perform bioinformatics analysis of wild-type and mutant ParC identified in S. pneumoniae strains. MATERIALS AND METHODS: Homology models were created with Swiss Model, and the UCSF Chimera was used for the analysis and evaluation of the models....

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PMID: 37606103
DOI: 10.26355/eurrev_202308_33265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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