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Article

Best practices for genotype imputation from low-coverage sequencing data in natural populations.

Molecular ecology resources - 1 Jul 2025

Watowich Marina M, Chiou Kenneth L, Graves Brian, Montague Michael J, Brent Lauren J N, Higham James P, Horvath Julie E, Lu Amy, Martinez Melween I, Platt Michael L, Schneider-Crease India A, Lea Amanda J, Snyder-Mackler Noah

Abstract excerpt

Monitoring genetic diversity in wild populations is a central goal of ecological and evolutionary genetics and is critical for conservation biology. However, genetic studies of nonmodel organisms generally lack access to species-specific genotyping methods (e.g. array-based genotyping) and must instead use sequencing-based approaches. Although costs are decreasing, high-coverage whole-genome sequencing (WGS),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37602981
DOI: 10.1111/1755-0998.13854
PMCID: PMC10879460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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