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Comparing antimicrobial resistant genes and phenotypes across multiple sequencing platforms and assays for Enterobacterales clinical isolates.

BMC microbiology - 18 Aug 2023

Rose Rebecca, Nolan David J, Ashcraft Deborah, Feehan Amy K, Velez-Climent Leonor, Huston Christopher, Lain Benjamin, Rosenthal Simon, Miele Lucio, Fogel Gary B, Pankey George, Garcia-Diaz Julia, Lamers Susanna L

Abstract excerpt

INTRODUCTION: Whole genome sequencing (WGS) of bacterial isolates can be used to identify antimicrobial resistance (AMR) genes. Previous studies have shown that genotype-based AMR has variable accuracy for predicting carbapenem resistance in carbapenem-resistant Enterobacterales (CRE); however, the majority of these studies used short-read platforms (e.g. Illumina) to generate sequence data. In this study, our...

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PMID: 37596530
DOI: 10.1186/s12866-023-02975-x
PMCID: PMC10436404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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