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Article

Identifying causal genes for migraine by integrating the proteome and transcriptome

17 Aug 2023

Abstract excerpt

BACKGROUND: While previous genome-wide association studies (GWAS) have identified multiple risk variants for migraine, there is a lack of evidence about how these variants contribute to the development of migraine. We employed an integrative pipeline to efficiently transform genetic associations to identify causal genes for migraine. METHODS: We conducted a proteome-wide association study (PWAS) by combining data...

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Share to Cerebrovascular and genetic disorders
Share to Glutathione Transferases and Polymorphisms
Share to Migraine and Headache Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37592229
DOI: 10.1186/s10194-023-01649-3

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