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Article

A cross-tissue transcriptome-wide association study reveals novel susceptibility genes for migraine.

The journal of headache and pain - 5 Jun 2024

Gui Jianxiong, Yang Xiaoyue, Tan Chen, Wang Lingman, Meng Linxue, Han Ziyao, Liu Jie, Jiang Li

Abstract excerpt

BACKGROUND: Migraine is a common neurological disorder with a strong genetic component. Despite the identification of over 100 loci associated with migraine susceptibility through genome-wide association studies (GWAS), the underlying causative genes and biological mechanisms remain predominantly elusive. METHODS: The FinnGen R10 dataset, consisting of 333,711 subjects (20,908 cases and 312,803 controls), was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38840241
DOI: 10.1186/s10194-024-01802-6
PMCID: PMC11151630

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