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Article

Integrating eQTL and GWAS data characterises established and identifies novel migraine risk loci.

Human genetics - 1 Aug 2023

Ghaffar Ammarah, Nyholt Dale R

Abstract excerpt

Migraine-a painful, throbbing headache disorder-is the most common complex brain disorder, yet its molecular mechanisms remain unclear. Genome-wide association studies (GWAS) have proven successful in identifying migraine risk loci; however, much work remains to identify the causal variants and genes. In this paper, we compared three transcriptome-wide association study (TWAS) imputation models-MASHR, elastic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37245199
DOI: 10.1007/s00439-023-02568-8
PMCID: PMC10449685

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