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Article

Identifying novel proteins for migraine by integrating proteomes from blood and CSF with genome-wide association data.

CNS neuroscience & therapeutics - 1 Jun 2024

Niu Peng-Peng, Zhang Rui, Zhang Chan, Li Shuo, Li Yu-Sheng

Abstract excerpt

BACKGROUND: Proteome-wide Mendelian randomization studies have been increasingly utilized to identify potential drug targets for diseases. We aimed to identify potential therapeutic targets for migraine and its subtypes through the application of Mendelian randomization and co-localization analysis methods. METHODS: We utilized cis-protein quantitative trait loci data for 1378 plasma proteins available from two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38898596
DOI: 10.1111/cns.14817
PMCID: PMC11186850

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