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Article

Integrative genetic analysis identifies shared regulation of DNA methylation and gene expression in migraine risk.

The journal of headache and pain - 31 Jul 2026

Ghaffar Ammarah, Nyholt Dale R

Abstract excerpt

BACKGROUND: Migraine affects approximately 14% of adults, but the molecular mechanisms underlying susceptibility remain incompletely understood. Although genome-wide association studies (GWAS) have identified many migraine risk loci, translating these associations into biological insight remains challenging. Environmental and physiological migraine triggers, including hormones, diet and stress, may act partly...

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Share to DNA Methylation
Share to Epigenesis, Genetic
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42642720
DOI: 10.1186/s10194-026-02469-x
PMCID: PMC13508431

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