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Article

Proteome-wide Mendelian randomization identified potential drug targets for migraine

11 Sept 2024

Abstract excerpt

BACKGROUND: Migraine is a highly prevalent and complex neurovascular disease. However, the currently available therapeutic drugs often fall to adequately meet clinical needs due to limited effectiveness and numerous undesirable side effects. This study aims to identify putative novel targets for migraine treatment through proteome-wide Mendelian randomization (MR). METHODS: We utilized MR to estimate the causal...

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PMID: 39261750
DOI: 10.1186/s10194-024-01853-9

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